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SC35 Mouse anti-Human, Unlabeled, Clone: ASC35, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 556363

Catalog No. BDB556363


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Description

Description

SC35 belongs to a highly conserved SR splicing factor family. Members of this family have characteristic RNA-binding domains and serine/arginine-rich (SR) motifs. SR proteins are expressed in the nucleus and are essential pre-messenger RNA splicing factors. Nuclear pre-messenger RNA takes place in spliceosomes, multicomponent complexes consisting of five small nuclear ribonucleoprotein particles (U1, U2, U4, U5, U6) and other non-snRNP factors such as SC35. SC35 is necessary for an early step in spliceosome assembly and can also influence the selection of alternative splice sites. SC35 is identified as a 35kDa protein in SDS/PAGE. Clone αSC35 has been shown to recognize SC35 in human, and rat cells. However, it should recognize SC35 from any species, as SC35 is conserved from Drosophila to man. Partially purified spliceosomes were used as immunogen.

Host Species: Mouse
Clone: αSC35
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Partially purified spliceosomes

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY
Specifications

Specifications

SC35
Monoclonal
0.5mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Partially purified spliceosomes
0.1 mg
Cell Biology
Human
IgG1 κ
Western Blot
ASC35
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C
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