SDHA Mouse anti-Bovine, Canine, Human, Mouse, Rat, Clone: 2E3GC12FB2AE2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen 459200
ICC application requires heat-induced antigen retrieval where aldehydes are used as fixatives. Use 20min incubation at 90-100°C in 0.1 M Tris/HCl pH 9.5 with 5% urea (wt/vol).|Positive control: Human heart mitochondria.SDHA is an important component in the citric acid cycle and respiratory chain. SDHA converts succinate to fumarate, transfers electrons in the respiratory chain, and ultimately transfers electrons to ubiquinone. SDHA is localized within the mitochondrial inner membrane. Mutations in the gene have been associated with Leigh syndrome and Huntington ft.s disease. However, SDHA also appears to have tumor suppressor effects.
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|HEPES buffered saline with 0.02% sodium azide|
|P31039, P31040, Q8K2B3, Q920L2|
|CMD1GG, FP, PGL5, SDH1, SDH2, SDHF, flavoprotein subunit of complex II, succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, succinate dehydrogenase complex flavoprotein subunit|
|157074, 281480, 6389, 66945|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|Full length native protein (purified) corresponding to Cow SDHA. Purified mitochondrial complex II (Cow).|
|Bovine, Canine, Human, Mouse, Rat|
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