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DHCR24 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527944

Catalog No. PIPA527944


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Description

Description

PA5-27944 targets Seladin 1 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples. The PA5-27944 immunogen is recombit fragment corresponding to a region within amino acids 55 and 358 of Human Seladin 1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Specifications

Specifications

DHCR24
Polyclonal
Unconjugated
DHCR24
Liquid
DHCR24
Recombit fragment corresponding to a region within amino acids 55 and 358 of Human Seladin 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.71 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q15392, Q8VCH6
DCE, Nbla03646, SELADIN1, seladin-1, 3 beta-hydroxysterol delta 24-reductase, 3-beta-hydroxysterol delta-24-reductase, delta(24)-sterol reductase, desmosterol-to-cholesterol enzyme, diminuto/dwarf1 homolog, seladin 1, selective AD indicator 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1718, 74754
Documents
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