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SEMA4A Mouse anti-Human, PE, Clone: T9-10, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564812

Catalog No. BDB564812


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Description

Description

The T9-10 monoclonal antibody specifically binds to Semaphorin 4A (SEMA4A/ SEM4A) which is also known as Semaphorin-B (Sema B/ SEMAB/SEMB). SEMA4A is a type I transmembrane glycoprotein that belongs to the class IV subfamily of the semaphorin family. A cleaved, soluble form of SEMA4A has also been described. It is expressed by B cells, dendritic cells, monocytes, granulocytes, and at low levels by some T cells. SEMA4A plays several roles in the immune system including the reciprocal activation of antigen presenting cells and T cells leading to the differentiation of effector CD4+ T cells. SEMA4A functions in the developing nervous system by guiding neuronal axons to their proper target cells. It is also involved in the regulation of angiogenesis and the progression of certain cancers.

Specifications

Specifications

SEMA4A
T9-10
PE
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG1, κ
100μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Semaphorin-4A; SEMA4A; SEM4A; Semaphorin-B; Sema B; SEMB; SEMAB; CORD10
Affinity Purified
Recombinant Human Semaphorin 4A Protein
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Human
Documents
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