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SEMA4A Mouse anti-Human, PE, Clone: T9-10, BD

Catalog No. BDB564812 Shop All BD Biosciences Products
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BDB564812 100 μg
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Catalog No. BDB564812 Supplier BD Biosciences Supplier No. 564812

Description

Mouse Monoclonal Antibody

The T9-10 monoclonal antibody specifically binds to Semaphorin 4A (SEMA4A/ SEM4A) which is also known as Semaphorin-B (Sema B/ SEMAB/SEMB). SEMA4A is a type I transmembrane glycoprotein that belongs to the class IV subfamily of the semaphorin family. A cleaved, soluble form of SEMA4A has also been described. It is expressed by B cells, dendritic cells, monocytes, granulocytes, and at low levels by some T cells. SEMA4A plays several roles in the immune system including the reciprocal activation of antigen presenting cells and T cells leading to the differentiation of effector CD4+ T cells. SEMA4A functions in the developing nervous system by guiding neuronal axons to their proper target cells. It is also involved in the regulation of angiogenesis and the progression of certain cancers.

TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA4A
Applications Flow Cytometry
Classification Monoclonal
Clone T9-10
Concentration 0.2mg/mL
Conjugate PE
Description Semaphorin-4A; SEMA4A; SEM4A; Semaphorin-B; Sema B; SEMB; SEMAB; CORD10
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human Semaphorin 4A Protein
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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