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MilliporeSigma™ anti-Serotonin 2A (5-HT2A) Receptor (22-41), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC176100UL

Catalog No. PC176100UL


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Description

Description

Specifically detects Serotonin 2A (5-HT2A) Receptor (22-41) Clone: in Mouse, Rat, Sheep samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting

At least 14 mammalian serotonin receptor subtypes have been identified and classified into several families on the basis of common structural, pharmacological, and functional criteria. Serotonin (5-hydroxytryptamine [5-HT]) mediates its effects in a number of physiological processes including anxiety, depression, sexual activity, and sleep through interactions with different receptor subtypes. These receptors differ in their tissue and cellular localization, affinity for serotonin, and second messenger pathways. The majority of these receptors stimulate a GTP-binding protein upon agonist stimulation and couple to adenylate cyclase or phospholipase C. In contrast, the serotonin 5-HT3 receptor acts as a cation-selective channel. The serotonin receptors have generated considerable pharmacological interest as targets for the identification of selective drugs that interact with a specific receptor subtype.
Specifications

Specifications

Serotonin 2A (5-HT2A) Receptor (22-41)
Unconjugated
Liquid
a synthetic peptide corresponding to amino acids 22-41 of rat 5-HT2A receptor
RUO
Primary
Recognizes the ∽53kDa serotonin 2A (5-HT2A) receptor.
Immuno Blotting, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
In 150mM NaCl, 20mM sodium phosphate, 1% BSA, pH 7.5.
Rabbit
100μL
−20°C
Polyclonal
Murine, Rat, Sheep
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