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MilliporeSigma™ anti-Serotonin 2A (5-HT2A) Receptor (22-41), Polyclonal

Catalog No. PC176100UL Shop All MilliporeSigma Products
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Quantity:
100 μL
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
PC176100UL 100 μL Unconjugated
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Catalog No. PC176100UL Supplier MilliporeSigma™ Supplier No. PC176100UL
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Description

Rabbit Polyclonal Antibody

Specifically detects Serotonin 2A (5-HT2A) Receptor (22-41) Clone: in Mouse, Rat, Sheep samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting

At least 14 mammalian serotonin receptor subtypes have been identified and classified into several families on the basis of common structural, pharmacological, and functional criteria. Serotonin (5-hydroxytryptamine [5-HT]) mediates its effects in a number of physiological processes including anxiety, depression, sexual activity, and sleep through interactions with different receptor subtypes. These receptors differ in their tissue and cellular localization, affinity for serotonin, and second messenger pathways. The majority of these receptors stimulate a GTP-binding protein upon agonist stimulation and couple to adenylate cyclase or phospholipase C. In contrast, the serotonin 5-HT3 receptor acts as a cation-selective channel. The serotonin receptors have generated considerable pharmacological interest as targets for the identification of selective drugs that interact with a specific receptor subtype.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Serotonin 2A (5-HT2A) Receptor (22-41)
Applications Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Formulation In 150mM NaCl, 20mM sodium phosphate, 1% BSA, pH 7.5.
Host Species Rabbit
Immunogen a synthetic peptide corresponding to amino acids 22-41 of rat 5-HT2A receptor
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽53kDa serotonin 2A (5-HT2A) receptor.
Target Species Mouse, Rat, Sheep
Content And Storage −20°C
Form Liquid
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For Research Use Only

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