SERPINC1 (M02A), Mouse anti-Human, Clone: 2B12, Abnova™

Catalog No.	Quantity
89-016-231	200 μL

Catalog No. 89-016-231 Supplier Abnova Corporation Supplier No. H00000462M02A

Description

Mouse monoclonal antibody raised against a full-length recombinant SERPINC1.

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq

Sequence: MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK

Specifications

• Antigen: SERPINC1
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2B12
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full-length recombinant SERPINC1.
• Formulation: ascites with no preservative
• Gene: SERPINC1
• Gene Accession No.: BC022309
• Gene Alias: AT3/ATIII/MGC22579
• Gene Symbols: SERPINC1
• Host Species: Mouse
• Immunogen: SERPINC1 (AAH22309.1, 1 a.a. ∼ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 462
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Ascites
• Isotype: IgG2b κ