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SHP2 Mouse, Unlabeled, Clone: 79, BD

Catalog No. BDB610621 Shop All BD Biosciences Products
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BDB610622 150 μg
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Catalog No. BDB610621 Supplier BD Biosciences Supplier No. 610621
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Description

Mouse Monoclonal Antibody

SHP2 (also known as PTP1D, Syp, SHPTP2 and PTP2C) is a member of the cytosolic class of protein-tyrosine phosphatases (PTPs). SHP2 has been reported to contain two SH2 domains where both SH2 domains are N-terminal to the PTP catalytic domain. The expression of SHP2 has been reported to be highest in brain, heart, and kidney. The PTPs are thought to function with other protein-tyrosine kinases to maintain intracellular protein phosphotyrosine homeostasis and cell cycle progression. The presence ofSH2 domains in SHP2 (PTP1D) has prompted speculation that binding to specific phosphorylated tyrosine residues is key to its function. SHP2 (PTP1D) is tyrosine- phosphorylated and activated in response to stimulation with EGF or PDGF.

TRUSTED_SUSTAINABILITY

Specifications

Antigen SHP2
Applications Western Blot
Classification Monoclonal
Clone 79
Concentration 250μg/mL
Conjugate Unconjugated
Description PTP1D, Syp, SHPTP2 and PTP2C
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Chicken, Frog, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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