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MilliporeSigma™ anti-SIGIRR Clone: 3H8-2G3,

Catalog No. ST1681200UL Shop All MilliporeSigma Products
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Quantity:
200 μL
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
ST1681200UL 200 μL Unconjugated
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Catalog No. ST1681200UL Supplier MilliporeSigma™ Supplier No. ST1681200UL
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Description

Mouse Monoclonal Antibody

Specifically detects SIGIRR Clone: 3H8-2G3 in Human samples, and it is validated for Immuno Blotting

The SIGIRR protein acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Its extracellular domain is known to interfere with the heterodimerization of Il1R1 and IL1RAP.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIGIRR
Applications Immunoblot
Classification Monoclonal
Clone 3H8-2G3
Conjugate Unconjugated
Formulation Undiluted ascites
Host Species Mouse
Immunogen Full-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
Purification Method Unpurified
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽32kDa SIGIRR protein in HepG2 cells.
Target Species Human
Content And Storage −20°C
Isotype IgM
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For Research Use Only

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