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SIGLEC9 Rabbit anti-Bovine, Canine, Equine, Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523503

Catalog No. PIPA523503


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Description

Description

Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- and NK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.
Specifications

Specifications

SIGLEC9
Polyclonal
Unconjugated
SIGLEC9
Liquid
LOC100062855, SIGLEC9
A portion of amino acids 40-90 of human Siglec9 was used as the immunogen
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Non-human Primate
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9Y336
UNQ668/PRO1302, CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9, protein FOAP-9, sialic acid-binding Ig-like lectin 9
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100062855, 27180
Documents
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