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SIPA1L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520848

Catalog No. PIPA520848


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-20848 can be used with blocking peptide PEP-0962.

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
Specifications

Specifications

SIPA1L2
Polyclonal
Unconjugated
SIPA1L2
Liquid
SIPA1L2
A 19 amino acid peptide from near the amino terminus of human SIPA1L2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9P2F8, Q80TE4, Q5JCS6
SPAL2; SIPA1-like protein 2; SPA-1-like 2; signal-induced proliferation-associated 1-like protein 2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
244668, 361442, 57568
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