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SIPA1L3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520849

Catalog No. PIPA520849


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Description

Description

A suggested positive control is SK-N-SH cell lysate. PA5-20849 can be used with blocking peptide PEP-0963.

Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
Specifications

Specifications

SIPA1L3
Polyclonal
Unconjugated
SIPA1L3
Liquid
SIPA1L3
A 15 amino acid peptide from near the amino terminus of human SIPA1L3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O60292, G3X9J0
SPAL3; SIPA1-like protein 3; SPA-1-like 3; SPA-1-like protein 3; signal-induced proliferation-associated 1-like protein 3
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
23094, 292771, 74206
Documents
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