MilliporeSigma™ anti-SKP1A Clone: 1H8,

Catalog No.	Quantity	Conjugate
ST1709100UG	100 μg	Unconjugated

Catalog No. ST1709100UG Supplier MilliporeSigma™ Supplier No. ST1709100UG

Description

Mouse Monoclonal Antibody

Specifically detects SKP1A Clone: 1H8 in Human samples, and it is validated for Immunocytochemistry

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Specifications

• Antigen: SKP1A
• Applications: Immunocytochemistry
• Classification: Monoclonal
• Clone: 1H8
• Conjugate: Unconjugated
• Formulation: In PBS, pH 7.2.
• Host Species: Mouse
• Immunogen: A recombinant polypeptide corresponding to amino acids of 53-161 human SKP1A, expressed as a GST fusion protein
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽18kDa SKP1A protein in HeLa cells.
• Target Species: Human
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG2a

For Research Use Only