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Description
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq
Specifications
Specifications
| Antigen | snail homolog 2 (Drosophila) |
| Applications | ELISA, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 3C12 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant SNAI2. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | SNAI2 |
| Gene Accession No. | NM_003068 |
| Gene Alias | MGC10182/SLUG/SLUGH1/WS2D |
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