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SNCA, Mouse, Clone: 2E4, Abnova™

Catalog No. 89123134 Shop All Abnova Corporation Products
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89-123-134 100 μg
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Catalog No. 89-123-134 Supplier Abnova Corporation Supplier No. H00006622M01
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Mouse monoclonal antibody raised against a partial recombinant SNCA.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Sequence: GKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA

Specifications

Antigen SNCA
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 2E4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant SNCA.
Formulation PBS with no preservative; pH 7.4
Gene SNCA
Gene Accession No. NM_000345
Gene Alias MGC110988/NACP/PARK1/PARK4/PD1
Gene Symbols SNCA
Host Species Mouse
Immunogen SNCA (NP_000336, 31 a.a. ∼ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6622
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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