SOCS2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human SOCS2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00008835K

Catalog No. 89-203-073

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: SOCS2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: SOCS2
• Gene Symbols: SOCS2
• Immunogen: A synthetic peptide of human SOCS2
• Regulatory Status: RUO
• Gene ID (Entrez): 8835
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: suppressor of cytokine signaling 2
• Gene: SOCS2
• Gene Alias: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid