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Description
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq
Specifications
Specifications
| Antigen | SOCS6 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a full-length human SOCS6 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | SOCS6 |
| Gene Accession No. | NM_004232 |
| Gene Alias | CIS4/HSPC060/SOCS4/SSI4/STAI4/STATI4 |
| Gene Symbols | SOCS6 |
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