SORBS2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human SORBS2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00008470K

Catalog No. 89-203-601

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Arg and c-Abl represent the mammalian members of the Abelson family of nonreceptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: SORBS2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: SORBS2
• Gene Symbols: SORBS2
• Immunogen: A synthetic peptide of human SORBS2
• Regulatory Status: RUO
• Gene ID (Entrez): 8470
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: sorbin and SH3 domain containing 2
• Gene: SORBS2
• Gene Alias: ARGBP2, FLJ93447, KIAA0777, PRO0618
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid