Learn More
Description
The monoclonal antibody O30-678 recognizes the Sox2 transcription factor. Sox2 [SRY (sex determining region Y)-box 2] is a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of Sox2 with the homeobox transcription factors Oct3/4 and/or Nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain. The O30-678 antibody recognizes both human and mouse Sox2 proteins.
Specifications
Specifications
| Antigen | Sox2 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | O30-678 |
| Conjugate | Alexa Fluor 488 |
| Formulation | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Sox2 Recombinant Protein |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.