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Sox7 Mouse anti-Human, PE, Clone: S5-1216, BD

Catalog No. BDB564695 Shop All BD Biosciences Products
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BDB564695 50 Tests
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Catalog No. BDB564695 Supplier BD Biosciences Supplier No. 564695

Description

Mouse Monoclonal Antibody

The S5-1216 monoclonal antibody specifically binds to human Sox7, a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox7 plays a key role in cardiac, hematopoietic and vascular development. Sox7 is also involved in endoderm lineage determination, where Sox7 is expressed in the extraembryonic endoderm but not in the definitive endoderm. Over-expression of Sox7 in human embryonic stem cells leads to differentiation into lineage restricted extraembryonic endoderm progenitors. Furthermore, Sox7 has a tumor suppressive activity, as indicated by its down-regulation in colon, prostate, lung and breast cancer.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Sox7
Applications Flow Cytometry
Classification Monoclonal
Clone S5-1216
Conjugate PE
Description Transcription factor SOX-7, SOX7
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Sox7 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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