spastic paraplegia 21 (autosomal recessive, Mast syndrome), Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant SPG21.
Manufacturer: Abnova Corporation H00051324A01
The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeqSequence: PHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQE
|spastic paraplegia 21 (autosomal recessive, Mast syndrome)|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant SPG21.|
|SPG21 (NP_057714, 211 a.a. ~ 306 a.a) partial recombinant protein with GST tag.|
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