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Description
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | SPG3A |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1B11 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant SPG3A. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | ATL1 |
| Gene Accession No. | NM_015915 |
| Gene Alias | AD-FSP/FSP1/GBP3/SPG3/SPG3A/atlastin1 |
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