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EDG3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523225

Catalog No. PIPA523225


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Description

Description

Edg3 is a member of the EDG family of receptors which acts as a major functional receptor for a potent, extracellular lysolipid phosphoric acid mediator, S1P. It is the major S1P receptor subtype in the cardiovascular system, where it mediate the effects of S1P released from platelets, and possibly other tissues (such as brain). The receptor thus enhances endothelial and vascular smooth muscle cell proliferation and migration, playing a key role in developmental and pathological angiogenesis. The protein also mediates S1P-induced inflammatory response genes expression and can be used as drug targets to treat severe inflammation. Edg3 is expressed in many cell types, including endothelial and vascular smooth muscle cells and most abundantly in heart, placenta, kidney, and liver. Human Edg3 gene is mapped to chromosome 9q22.1-q22.2.
Specifications

Specifications

EDG3
Polyclonal
Unconjugated
S1PR3
Liquid
S1PR3
Synthetic peptide (326 SPIQPALDPSRSKSSSSNNSS 346) of Sphingolipid Receptor Edg3/S1P3 protein.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q99500, Q9Z0U9
EDG-3, EDG3, LPB3, S1P3, G protein-coupled receptor, endothelial differentiation gene-3, S1P receptor 3, S1P receptor EDG3, S1P receptor Edg-3, endothelial differentiation G-protein coupled receptor 3, endothelial differentiation, sphingolipid G-protein-coupled receptor, 3, sphingosine 1-phosphate receptor 3, sphingosine 1-phosphate receptor Edg-3
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
13610, 1903
Documents
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