SGMS1, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA112762

Catalog No. 01-675-784

Description

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

A suggested positive control for this product is brain, heart, kidney, liver, muscle or stomach lysate.

Specifications

• Antigen: SGMS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q86VZ5
• Gene Symbols: SGMS1
• Immunogen: Full-length recombinant sphingomyelin synthase 1 fusion protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg/mL
• Gene: SGMS1
• Gene Alias: MGC17342, MOB, MOB1, SMS1, TMEM23, hmob33
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 259230
• Content And Storage: Store at -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid