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SPHK2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112872

Catalog No. 01-675-852


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Description

Description

Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

A suggested positive control for this product is Jurkat cell lysate.
Specifications

Specifications

SPHK2
Polyclonal
PBS with 0.08% sodium azide
Q9NRA0
SPHK2
Synthetic peptide corresponding to the N-terminal extension of Sphingosine Kinase 2-L.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Western Blot
Unconjugated
SPHK2
Liquid
Rabbit
IgG
10 Miniblots
-80° C, Avoid Freeze/Thaw Cycles
Primary
56848
Documents
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