SPTLC2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human SPTLC2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00009517K

Catalog No. 89-203-311

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: SPTLC2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: SPTLC2
• Gene Symbols: SPTLC2
• Immunogen: A synthetic peptide of human SPTLC2
• Regulatory Status: RUO
• Gene ID (Entrez): 9517
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: serine palmitoyltransferase, long chain base subunit 2
• Gene: SPTLC2
• Gene Alias: KIAA0526, LCB2, SPT2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid