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sequestosome 1, Mouse, Clone: 2C11, Abnova™

Catalog No. 89015843 Shop All Abnova Corporation Products
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89-015-843 100 μg
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Catalog No. 89-015-843 Supplier Abnova Corporation Supplier No. H00008878M01
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Description

Mouse monoclonal antibody raised against a full-length recombinant SQSTM1.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NFkb in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq

Sequence: MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

Specifications

Antigen sequestosome 1
Applications ELISA, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 2C11
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full length recombinant SQSTM1.
Formulation PBS with no preservative; pH 7.4
Gene SQSTM1
Gene Accession No. BC003139
Gene Alias A170/OSIL/PDB3/ZIP3/p60/p62/p62B
Gene Symbols SQSTM1
Host Species Mouse
Immunogen SQSTM1 (AAH03139.1, 1 a.a. ∼ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 8878
Target Species Human, Mouse
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG2a κ
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