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Src (pY418) Mouse, Alexa Fluor 488, Clone: K98-37, BD

Catalog No. BDB560095 Shop All BD Biosciences Products
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BDB560095 50 Tests
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Catalog No. BDB560095 Supplier BD Biosciences Supplier No. 560095

Description

Mouse Monoclonal Antibody

The non-receptor protein tyrosine kinases of the Src family have similar domain structures with considerable sequence homologies. They are associated with cell membranes and are activated by a wide variety of cell-surface receptors. Through their participation in cell-signaling cascades that mediate an array of cellular responses, they control essential cellular activities.

Src, the prototype of the Src family, is encoded by the SRC protooncogene, which is a homolog of the v-Src

The K98-37 monoclonal antibody recognizes the phosphorylated Y418 in the protein kinase domain of activated Src. The orthologous phosphorylation sites in chicken, mouse, and rat Src are Y415, Y423, and Y418, respectively. Because of sequence similarities in this region, it may also recognize the homologous sites of some other Src family members: Lyn (pY396), Fyn (pY420), Hck (pY410), Lck (pY394), and Yes (pY425).

TRUSTED_SUSTAINABILITY

Specifications

Antigen Src (pY418)
Applications Flow Cytometry
Classification Monoclonal
Clone K98-37
Conjugate Alexa Fluor 488
Description c-Src, p60-Src, SRC, SRC1
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Phosphorylated Human Src Peptide
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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