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SSEA-3 Rat, FITC, Clone: MC631, BD

Catalog No. BDB560236 Shop All BD Biosciences Products
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Rat Monoclonal Antibody

The MC631 monoclonal antibody reacts with Stage-Specific Embryonic Antigen-3 (SSEA-3), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of mouse embryos and human teratocarcinoma cells. As its name implies, the expression of SSEA-3 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-3 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), and embryonic stem (ES) cells, and erythrocytes. As human stem cells undergo differentiation, SSEA-3 expression diminishes. In the mouse, SSEA-3 is found on oocytes, ova, zygotes, early cleavage-stage embryos, early blastocysts, ICM, primitive endoderm, and adult kidney, but not on EC or ES cells.

Host Species: Rat
Clone: MC631
Isotype: IgM
Species Reactivity: Human
Immunogen: Mouse Embryos

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen SSEA-3
Applications Flow Cytometry
Classification Monoclonal
Clone MC631
Conjugate FITC
Formulation Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse Embryos
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgM
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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