SSEA-3 Rat, PE, Clone: MC631, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 560237

Catalog No. BDB560237

Description

The MC631 monoclonal antibody reacts with Stage-Specific Embryonic Antigen-3 (SSEA-3), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of mouse embryos and human teratocarcinoma cells. As its name implies, the expression of SSEA-3 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-3 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), and embryonic stem (ES) cells, and erythrocytes. As human stem cells undergo differentiation, SSEA-3 expression diminishes. In the mouse, SSEA-3 is found on oocytes, ova, zygotes, early cleavage-stage embryos, early blastocysts, ICM, primitive endoderm, and adult kidney, but not on EC or ES cells.

Host Species: Rat
Clone: MC631
Isotype: IgM
Species Reactivity: Human
Immunogen: Mouse Embryos

Flow Cytometry

Specifications

• Antigen: SSEA-3
• Classification: Monoclonal
• Conjugate: PE
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: MC631
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Mouse Embryos
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Human, Mouse
• Isotype: IgM

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov