SSEA-4 Mouse, PE, Clone: MC813-70, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560128

Catalog No. BDB560128

Description

The MC813-70 monoclonal antibody reacts with Stage-Specific Embryonic Antigen-4 (SSEA-4), a carbohydrate epitope on the major ganglioside, but not the neutral glycolipid, of human teratocarcinoma cells. As its name implies, the expression of SSEA-4 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-4 is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (ICM), and embryonic stem (ES) cells, erythrocytes, and the K562 erythromyeloid leukeumia cell line. As human stem cells undergo differentiation, SSEA-4 expression is lost. In the mouse, SSEA-4 is found on oocytes and early cleavage-stage embryos, and primitive ectoderm, but not on EC, ICM, or ES cells. In some cases, SSEA-4 expression appears upon differentiation of mouse EC or ES cells.

Host Species: Mouse
Clone: MC813-70
Isotype: IgG3, κ
Species Reactivity: Human
Immunogen: Human Teratocarcinoma Cell Line

Flow Cytometry

Specifications

• Antigen: SSEA-4
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Immunogen: Human Teratocarcinoma Cell Line
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Human, Mouse
• Isotype: IgG3 κ

• Applications: Flow Cytometry
• Clone: MC813-70
• Description: Stage-Specific Embryonic Antigen-4
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.