stanniocalcin 2, Mouse, Clone: 2B11, Abnova™

Catalog No.	Quantity
89-019-166	100 μg

Catalog No. 89-019-166 Supplier Abnova Corporation Supplier No. H00008614M08

Description

Mouse monoclonal antibody raised against a full-length recombinant STC2.

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq

Sequence: MCAERLGQFMTLALVLATFDPARGTDATNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR

Specifications

• Antigen: stanniocalcin 2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2B11
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant STC2.
• Formulation: PBS with no preservative; pH 7.4
• Gene: STC2
• Gene Accession No.: BC000658
• Gene Alias: STC-2/STCRP
• Gene Symbols: STC2
• Host Species: Mouse
• Immunogen: STC2 (AAH00658, 1 a.a. ∼ 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Signal Transduction
• Primary or Secondary: Primary
• Gene ID (Entrez): 8614
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG2b κ