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Striatin Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610838

Catalog No. BDB610838


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Description

Description

Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein
identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of
proteins with the repeated WD motif (the β-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds
calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly
enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated
with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.

Immunofluorescence, Western Blotting

Specifications

Specifications

Striatin
6
Unconjugated
Affinity Purified
Rat Striatin aa. 450-600
50μg
Cell Biology
Primary
Canine, Human, Murine, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG2b
RUO
Store undiluted at -20°C.
Monoclonal
Documents
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