Striatin Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610838

Catalog No. BDB610838

Description

Signal transmission between neurons is regulated by the Ca²⁺-dependent release of neurotransmitters at the synapse. Striatin is a protein
identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of
proteins with the repeated WD motif (the β-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds
calmodulin in a Ca²⁺-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly
enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated
with the plasma membrane. Thus, striatin may play an important role in the Ca²⁺-dependent events occurring at the synapse.

Immunofluorescence, Western Blotting

Specifications

• Antigen: Striatin
• Clone: 6
• Conjugate: Unconjugated
• Format: Affinity Purified
• Immunogen: Rat Striatin aa. 450-600
• Quantity: 50μg
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Canine, Human, Murine, Rat

• Applications: Western Blot
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Host Species: Mouse
• Isotype: IgG_2b
• Regulatory Status: RUO
• Storage Requirements: Store undiluted at -20°C.
• Monoclonal or Polyclonal: Monoclonal