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Striatin Mouse, Unlabeled, Clone: 6, BD

Catalog No. BDB610838 Shop All BD Biosciences Products
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BDB610838 50 μg
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Catalog No. BDB610838 Supplier BD Biosciences Supplier No. 610838
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Description

Mouse Monoclonal Antibody

Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein
identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of
proteins with the repeated WD motif (the β-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds
calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly
enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated
with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.

Immunofluorescence, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Striatin
Applications Western Blot
Classification Monoclonal
Clone 6
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat Striatin aa. 450-600
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2b
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