MilliporeSigma™ anti-SV40 T Antigen Clone: PAb280,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ DP14L100UG

Catalog No. DP14L100UG

Description

Specifically detects SV40 T Antigen Clone: PAb280 in SV40 infected cells samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting

Both the SV40 large T and small T antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular transforming protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the p105 product of the retinoblastoma susceptibility gene.

Specifications

• Antigen: SV40 T Antigen
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Simian virus 40 (SV40)
• Form: Purified

• Applications: Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
• Clone: PAb280
• Formulation: Lyophilized from a volatile buffer, 100μg BSA.
• Immunogen: the SV40 small T-antigen
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽21kDa SV40 small T-antigen in SV80 cells. Does not cross-react with SV40 large T-antigen.
• Content And Storage: 2°C to 8°C
• Isotype: IgG1

For Research Use Only