MilliporeSigma™ anti-SV40 T Antigen Clone: PAb419,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ DP01100UG

Catalog No. DP01100UG

Description

Specifically detects SV40 T Antigen Clone: PAb419 in samples, and it is validated for Immunofluorescence, Immunoprecipitation

SV40 T Ag (Ab-1) is a mouse monoclonal antibody with specificity for antigenic determinants localized to the amino terminal domain of the SV40 large T antigen. The sequences recognized by this reagent are also present on SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

Specifications

• Antigen: SV40 T Antigen
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C
• Isotype: IgG2a

• Applications: Immunofluorescence, Immunoprecipitation
• Clone: PAb419
• Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin.
• Immunogen: the N-terminal domain of SV40 large and small T-antigen
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽94kDa SV40 large T antigen and the ∽21kDa SV40 small T antigen.
• Form: Purified

For Research Use Only