Synaptophysin Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527286
PA5-27286 targets Synaptophysin in Western blot, immunocytochemistry, and immunohistochemistry (paraffin) applications and shows reactivity with Human, Rat and mouse samples. The PA5-27286 immunogen is recombit fragment corresponding to a region within amino acids 170 and 313 of Human Synaptophysin. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
|Recombit fragment corresponding to a region within amino acids 170 and 313 of Human Synaptophysin|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.025% Proclin 300; pH 7|
|P08247, Q62277, P07825|
|MRXSYP, major synaptic vesicle protein P38|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|20977, 24804, 6855|
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