CD138 Rat anti-Human, APC, Clone: 359103, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523540
In direct ELISAs, this antibody shows approximately 60% cross-reactivity with recombit mouse (rm) Syndecan-1 and no cross-reactivity with recombit human (rh) Syndecan-2, rhSyndecan-3, or rmSyndecan-4.CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
|Mouse myeloma cell line NS0-derived recombit human Syndecan-1/CD138 Gln18-Glu251|
|Buffered saline solution with BSA and 0.09% sodium azide|
|SDC1, SYND1, SDC, CD antigen 138|
|4° C, store in dark, DO NOT FREEZE!|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok