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Syntaxin 1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528431

Catalog No. PIPA528431


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Description

Description

PA5-28431 targets Syntaxin 1a in WB applications and shows reactivity with Human samples. The PA5-28431 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 43 of Human Syntaxin 1a. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).
Specifications

Specifications

Syntaxin 1
Polyclonal
Unconjugated
STX1A
Liquid
STX1A
Synthetic peptide corresponding to a region within amino acids 1 and 43 of Human Syntaxin 1a
Protein A
RUO
Antibody
Polyclonal
Human
Western Blot
9.3 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q16623
HPC-1, P35-1, STX1, SYN1A, neuron-specific antigen HPC-1, syntaxin-1A
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6804
Documents
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