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Tau Mouse anti-Rat, Unlabeled, Clone: TAU-5, BD

Catalog No. BDB556319 Shop All BD Biosciences Products
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BDB556319 0.1 mg
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Catalog No. BDB556319 Supplier BD Biosciences Supplier No. 556319
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Description

Mouse Monoclonal Antibody

Tau proteins are microtuble-associated proteins (MAPs) that are thought to function by stabilizing microtubles. They comprise a family of multiple polypeptides that originate from one gene. Alternate splicing of Tau mRNA and differential phosphorylation contribute to the heterogeneity of Tau. Typically, Tau proteins migrate between ∽45-70kDa with isoelectric points ranging from 6.5-8.0. Tau expression is widespread in the brain and is found in most cell types within the mammalian central nervous system. Tau has a complex biochemical nature that is partly due to its many isoforms. The number and molecular weights of Tau forms changes during brain development. Additionally, the molecular wieghts and forms of Tau proteins at a given point of development vary between species. Antibodies directed against different epitopes have been used to distinguish between Tau forms. The monoclonal antibody TAU-5 recognizes a phosphorylation-independent epitope on Tau proteins. The reduced molecular weight of Tau proteins may range between 45kDa to 95kDa. The TAU-5 antibody reacts with a phosphorylation-independent epitope in the middle of tau. It recognizes both the phosphorylated and non-phosphorylated form of Tau. The antibody has been characterized in rat tissue.

Host Species: Mouse
Clone: TAU-5
Isotype: IgG1
Species Reactivity: Rat

Immunohistochemistry, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Tau
Applications Western Blot
Classification Monoclonal
Clone TAU-5
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1
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For Research Use Only.

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