MilliporeSigma anti-TCF-4 Alexa Fluor 488, Clone: 6H5-3,
Mouse Monoclonal Antibody
Manufacturer: MilliporeSigma 05511AF488
Specifically detects TCF-4 Clone: 6H5-3 in Human, Mouse, Rat samples, and it is validated for ImmunocytochemistryTranscription factor 7-like 2 (UniProt Q9NQB0; also known as HMG box transcription factor 4, hTCF-4, T-cell factor 4, T-cell-specific transcription factor 4, TCF-4) is encoded by the TCF7L2 (also known as TCF4) gene (Gene ID 6934) in human. TCF4, also known as TCF7L2, is expressed widely during development. Gene targeting study indicates that it is required to maintain the crypt stem cells of the small intestine. TCF4 has many different splicing isoforms and they are expressed differentially in tissues and in cancers of different stages. Studies also indicate that variant of the TCF4 gene confers an increased risk of type 2 diabetes.
|Purified mouse antibody conjugate in PBS with 15mg/ml BSA and 0.1 % sodium azide.|
|Alexa Fluor 488|
|Amino acids 31-331 of human TCF-4.|
|Protein G purified|
|2°C to 8°C for one year from date of shipment|
|Human, Murine, Rat|
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