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MilliporeSigma™ anti-TCF-4 Alexa Fluor 647, Clone: 6H5-3,

Mouse Monoclonal Antibody

Manufacturer:  MilliporeSigma™ 05511AF647

Catalog No. 05-511-AF647M


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Description

Description

Specifically detects TCF-4 Clone: 6H5-3 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry

Transcription factor 7-like 2 (UniProt Q9NQB0; also known as HMG box transcription factor 4, hTCF-4, T-cell factor 4, T-cell-specific transcription factor 4, TCF-4) is encoded by the TCF7L2 (also known as TCF4) gene (Gene ID 6934) in human. TCF4, also known as TCF7L2, is expressed widely during development. Gene targeting study indicates that it is required to maintain the crypt stem cells of the small intestine. TCF4 has many different splicing isoforms and they are expressed differentially in tissues and in cancers of different stages. Studies also indicate that variant of the TCF4 gene confers an increased risk of type 2 diabetes.
Specifications

Specifications

TCF-4
6H5-3
Purified mouse antibody conjugate in PBS with 15mg/ml BSA and 0.1 % sodium azide.
Purified
Murine
IgG2a
100μL
Signaling
Primary
CAB97213.1
Immunocytochemistry
Alexa Fluor 647
Q9NQB0
TCF7L2, TCF4
Amino acids 31-331 of human TCF-4.
Protein G purified
RUO
2°C to 8°C for one year from date of shipment
Monoclonal
Human, Murine, Rat
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