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Description
This gene encodes transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq]
Specifications
Specifications
| Antigen | transcription factor 4 |
| Applications | ELISA, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 3E10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full length recombinant TCF4. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | TCF4 |
| Gene Accession No. | BC031056.1 |
| Gene Alias | E2-2/ITF2/MGC149723/MGC149724/PTHS/SEF2/SEF2-1/SEF2-1A/SEF2-1B/bHLHb19 |
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