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TCRγδ Mouse anti-Human, Brilliant Violet 650, Clone: B1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564156

Catalog No. BDB564156


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Description

Description

The B1 monoclonal antibody specifically binds to the γδ T cell receptor ( γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γchain (45-60 kDa) and a δ subunit (40-60 kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

Specifications

Specifications

TCRγδ
B1
Brilliant Violet 650
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
Affinity Purified
IgG1, κ
RUO
Primary
Human
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