TCR β chain Hamster anti-Mouse, FITC, Clone: H57-597, BD

Hamster Monoclonal Antibody

Supplier:  BD Biosciences 553171

Catalog No. BDB553171

Description

The H57-597 antibody reacts with a common epitope of the β; chain of the T-cell Receptor (TCR) complex on α;β; TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδ TCR-bearing T cells. In the fetal and adult thymus, the TCR β; -chain may form homodimers or pair with the pre-TCR α; -chain on the surface of immature thymocytes before expression of the TCR α; -chain. Plate-bound or soluble H57-597 antibody activates α;β; TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.

Specifications

• Antigen: TCR β chain
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2

• Applications: Flow Cytometry
• Clone: H57-597
• Conjugate: FITC
• Host Species: Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.