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TCR γδ Mouse anti-Human, PE-CF594, Clone: B1, BD

Catalog No. BDB562511 Shop All BD Biosciences Products
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BDB562511 50 μg
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Catalog No. BDB562511 Supplier BD Biosciences Supplier No. 562511
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Description

Mouse Monoclonal Antibody

The B1 monoclonal antibody specifically binds to the γδ T cell receptor (γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γ chain (45-60kDa) and a δ subunit (40-60kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ T cells may also play roles in antigen presentation and the regulation of autoimmune responses. Due to the fact that CD3 and γδ TCR antibodies may recognize epitopes which are very close to each other and that CD3 was interfering with the clone B1 antibody binding but not with the clone 11F2 antibody, we recommend to use clone 11F2 antibody to perform double staining of γδ TCR and CD3. This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter).

Host Species: Mouse
Clone: B1
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen TCR γδ
Applications Flow Cytometry
Classification Monoclonal
Clone B1
Concentration 0.2mg/mL
Conjugate PE-CF594
Description TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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