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Description
The B1 monoclonal antibody specifically binds to the γδ T cell receptor (γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γ chain (45-60kDa) and a δ subunit (40-60kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets ( γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ T cells may also play roles in antigen presentation and the regulation of autoimmune responses.
Host Species: Mouse
Clone: B1
Isotype: IgG1, κ
Species Reactivity: Human
Flow Cytometry
Specifications
Specifications
| Antigen | TCRγδ |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | B1 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 421 |
| Description | TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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