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Description
Anti-terminal-deoxynucleotidyl transferase (TdT) recognizes a 60kDa polymerase, a nuclear enzyme that catalyzes the template-independent addition of nucleotides to single-stranded DNA primers. It has been reported that TdT is involved in the regulation or translocation or both of DNA and gene rearrangement during normal T- and B-cell development.TdT is present in nuclei of immature T and B lymphocytes found in normal thymus and bone marrow. Some neoplastic cells of acute lymphoblastic lymphoma/leukemia have been shown to have high TdT activity. Mature lymphocytes from normal peripheral blood usually do not contain the enzyme.
Applications:
Flow Cytometry, Intracellular Staining
Specifications
Specifications
| Antigen | Terminal Transferase |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | E17-1519 |
| Concentration | 6.0μg/mL |
| Conjugate | PE |
| Formulation | Phosphate buffered saline with gelatin and 0.1% sodium azide. |
| Host Species | Mouse |
| Immunogen | Purified Human TdT |
| Quantity | 50 Tests |
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Safety and Handling
For Research Use Only.
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