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Description
This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. [provided by RefSeq
Specifications
Specifications
| Antigen | TFAM |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human TFAM protein. |
| Formulation | No additive |
| Gene | TFAM |
| Gene Accession No. | NM_003201.1 |
| Gene Alias | MtTF1/TCF6/TCF6L1/TCF6L2/TCF6L3/mtTFA |
| Gene Symbols | TFAM |
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