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TFE3 Mouse anti-Mouse, Unlabeled, Clone: G138-312, BD

Catalog No. BDB554263 Shop All BD Biosciences Products
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Catalog No. BDB554263 Supplier BD Biosciences Supplier No. 554263
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Description

Mouse Monoclonal Antibody

TFE3 is a ubiquitously expressed 50kDa transcription factor containing both basic helix-loop-helix (bHLH) and leucine zipper (ZIP) motifs. It was initially identified as a protein which bound to the μE3 site in the immunoglobulin heavy chain enhancer. In addition, it binds to the MLTF/USF site in the adenovirus major late promoter. Upon binding as a dimer, it induces a minor groove-oriented bend in the DNA, similar to other HLH proteins such as TFEB, USF, myc, and max. Binding results in transcriptional activation and is mediated through the basic region located just N-terminal to the HLH domain. Clone G138-312 recognizes TFE3. The antibody was raised against a bacterially expressed TFE3-L protein consisting of 327 amino acids encoded by nucleotides 361-2469 of the cloned cDNA.

Host Species: Mouse
Clone: G138-312
Isotype: IgG1
Species Reactivity: Human
Immunogen: TFE3-L Protein
Formula Weight [Chemical]: 50kDa

Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen TFE3
Applications Western Blot
Classification Monoclonal
Clone G138-312
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen TFE3-L Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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