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Description
Includes
Up to three rabbit IgG clones of 1mg each will be delivered to customer.
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq
Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
Specifications
| Antigen | TFPI |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1mg |
| Conjugate | Unconjugated |
| Description | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| Formulation | In 1X PBS, pH 7.4 |
| Gene | TFPI |
| Gene Accession No. | TFPI |
| Gene Alias | EPI, LACI, TFI, TFPI1 |
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