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TIM-1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA186790

Catalog No. PA186790


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Description

Description

In Western blot, this antibody detects a band at ~49kDa in human uterus tissue lysate. Rabbit anti TIM-1 antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry, it is also known as the hepatitis A virus cellular receptor- HAVCR (Curtiss and Colgan 2007), TIM -1 also acts as a receptor for other viruses, including Dengue, Ebola and Marburg (Kondratowicz et al. 2011).

The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.
Specifications

Specifications

TIM-1
Polyclonal
Unconjugated
HAVCR1
Liquid
HAVCR1
16 amino acid peptide sequence near the center of human TIM-1.
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q96D42, Q5QNS5, O54947
HAVCR, HAVCR-1, KIM-1, KIM1, TIM-1, TIM1, TIMD1
Rabbit
IgG
100 μg
4°C or -20°C if preferred
Primary
171283, 26762, 286934
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